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Lnp only affects the abundance of three-way junctions and tubules. We suggest a model in which ATL-mediated fusion counteracts the instability of free tubule ends.

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Lnp only affects the abundance of three-way junctions and tubules. We suggest a model in which ATL-mediated fusion counteracts the instability of free tubule ends. eLife is a peer-reviewed open access scientific journal for the biomedical and life sciences. It was established at the end of 2012 by the Howard Hughes Medical 

Limited understanding of infant pain has led to its lack of recognition in clinical practice. While the network of brain regions that encode the affective and sensory aspects of adult pain are well described, the brain structures involved in…

The critical aspect of the analysis is to determine, for a fixed number of code words, how to segment the odor concentration range so that mutual information is maximized. To explore the effects of lack of sleep on social behaviors, and in particular on aggression, Kayser et al. disrupted the sleep of male fruit flies using various techniques, such as shaking them during the night, and then observed how they… Building on previous work (Shi et al., 2013), we have used MicroED to determine the structure of catalase at 3.2 Å resolution from a single crystal. Adapting single-digit movements in opposite directions makes people open their grip in accordance with the adaptations of the individual digits, showing that grip aperture arises from goal-directed movements of the digits rather than being… It remains unclear how cytoskeletal filaments and motor proteins organize into cellular scale structures and how molecular properties of cytoskeletal components affect the large scale behaviors of these systems. One of the signals going the other way, from the brain to the bladder, is the activation of a part of the brainstem called the PMC, short for pontine micturition center. (The word 'micturition' originally referred to the urge to urinate… Determining how neurons along a sensorimotor circuit contribute to this transformation is central to understanding behavior.

Lnp only affects the abundance of three-way junctions and tubules. We suggest a model in which ATL-mediated fusion counteracts the instability of free tubule ends.

It remains unclear how cytoskeletal filaments and motor proteins organize into cellular scale structures and how molecular properties of cytoskeletal components affect the large scale behaviors of these systems. One of the signals going the other way, from the brain to the bladder, is the activation of a part of the brainstem called the PMC, short for pontine micturition center. (The word 'micturition' originally referred to the urge to urinate… Determining how neurons along a sensorimotor circuit contribute to this transformation is central to understanding behavior. Insect specific olfactory receptors are not an adaptation to a terrestrial insect lifestyle, but evolved later in insect evolution. Lnp only affects the abundance of three-way junctions and tubules. We suggest a model in which ATL-mediated fusion counteracts the instability of free tubule ends. As Open access (OA) is often perceived as the end goal of scholarly publishing, much research has focused on flipping subscription journals to an OA model. Focusing on what can happen after the presumed finish line, this study identifies… We also tested the involvement of the neuropeptide PDF and its receptors, which were reported to genetically interact with the npr-1 pathway and are required for npr-1–mediated elevation of locomotor activity (25).

One possible mechanism to explain why different biochemical responses occur at different concentrations of EGF is shown in (B). Following the addition of low doses of EGF, only the highest affinity adaptors can bind to the phosphorylated…

Many other R folks also publish on top of this all in the Journal of Statistical Software, or a “vignette”, to give examples of how to use packages (the eLife MorphoGraphX article is probably closest to a vignette). The cells of a cyanobacterium act as spherical micro-lenses, allowing the cell to see a light source and move towards it. (A) Principal component analysis of individuals according to the fraction of derived alleles that each individual carries in each of 96 mutational types. (B) Heatmaps showing, for pairs of continental groups, the ratio of the proportions of… One possible mechanism to explain why different biochemical responses occur at different concentrations of EGF is shown in (B). Following the addition of low doses of EGF, only the highest affinity adaptors can bind to the phosphorylated… Then, how does the population of scientists contributing to the Frontiers series of journals compare to other scientometric populations? We are finally seeing research into how toothed whales (porpoises, dolphins, and larger whales such as the sperm whale with teeth instead of baleen) use sonar to solve their own problems, and this work reveals unsuspected flexibility and… How cells cope with the stress of poorly folded proteins is the theme of a second article, which uncovers how fission yeast deploys the same cellular machinery in an unusual and very different way from other organisms.

Now, in eLife, Thomas Schilling of the University of California, Irvine and colleagues – Arul Subramanian (UC Irvine) as first author, Lauren Kanzaki (UC Irvine), and Jenna Galloway (Massachusetts General Hospital) – demonstrate that… We show that small lateral ventral neurons (sLNvs), a subset of PDF neurons, activate the dorsal neurons 2 (DN2s), the main circadian clock cells that regulate temperature preference rhythm (TPR). Limited understanding of infant pain has led to its lack of recognition in clinical practice. While the network of brain regions that encode the affective and sensory aspects of adult pain are well described, the brain structures involved in… Optogenetic inhibition demonstrates that the cortex is necessary and sufficient for the initiation and execution of a learned, skilled action. Such combinations of evolutionary questions and molecular methods should rapidly advance cancer research, and may one day tell us how to prevent cancers if possible and treat them if necessary.

Electron microscopy has been used to produce the first three-dimensional image of the PRC2 gene-silencing complex. Both nectar and scent are highly variable in native populations of coyote tobacco, Nicotiana attenuata, with some producing no nectar at all, uncorrelated with the tobacco's main floral attractant, benzylacetone. The denominator of Equation 4 is necessarily positive (proof in Supplemental Material, file "SuppMat_2019-06-20.pdf") and indicates that the overall correlation between the allelic turnover rate and the probability of functionalization… The critical aspect of the analysis is to determine, for a fixed number of code words, how to segment the odor concentration range so that mutual information is maximized. To explore the effects of lack of sleep on social behaviors, and in particular on aggression, Kayser et al. disrupted the sleep of male fruit flies using various techniques, such as shaking them during the night, and then observed how they… Building on previous work (Shi et al., 2013), we have used MicroED to determine the structure of catalase at 3.2 Å resolution from a single crystal.

1 Mar 2018 F The article “Who's downloading pirated papers? 2015, Sci-Hub ceased archiving articles in PeerJ, eLife, and PLOS journals, i.e. user successfully downloaded PDF with that DOI … unresolved requests are not saved”.

All articles are screened on submission for offensive, dangerous, and/or bioRxiv provides metrics for article views, PDF downloads, and attention scores. 1 Mar 2018 F The article “Who's downloading pirated papers? 2015, Sci-Hub ceased archiving articles in PeerJ, eLife, and PLOS journals, i.e. user successfully downloaded PDF with that DOI … unresolved requests are not saved”. 3 Jul 2018 This blog post was originally published on the eLife Sciences website. is that conventional document formats (e.g. Word, PDF and LaTeX) do not support the Stencila's article editor builds on Texture, an open source editor built for visually editing Download Stencila Desktop and take it for a test drive. Download PDF via a smartphone application (enhanced LiFE, eLiFE) or by use of paper manuals (adapted LiFE, aLiFE). Article has an altmetric score of 1. 5 May 2015 Several online-only journals publish articles that have article numbers If we downloaded and read a PDF article, we can report a page range